|
|
H+ + cis-aconitate <=> CO2 + Itaconate
|
4.1.1.6
cis-aconitate decarboxylase
|
–
|
MK
|
|
BRENDA:
BR320
KEGG:
R02243
MetaCyc:
ACONITATE-DECARBOXYLASE-RXN
|
|
|
|
trans-aconitate + H+ <=> Itaconate + CO2
|
4.1.1.113
trans-aconitate decarboxylase
|
–
|
MK
|
|
BRENDA:
BR52552
KEGG:
R11749
MetaCyc:
RXN-19902
|
|
|
|
Itaconate + GTP + CoA <=> itaconyl-CoA + GDP + phosphate
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
M
|
|
BRENDA:
BS417070
KEGG:
R02405
MetaCyc:
RXN-8988
|
|
|
|
ATP + Itaconate + CoA <=> ADP + phosphate + itaconyl-CoA
|
6.2.1.5
succinate---CoA ligase (ADP-forming)
|
–
|
K
|
|
BRENDA:
BS416615
KEGG:
R02404
|
|
|
|
succinyl-CoA + Itaconate <=> succinate + itaconyl-CoA
|
2.8.3
2.8.3.20
succinyl-CoA---D-citramalate CoA-transferase
2.8.3.22
succinyl-CoA---L-malate CoA-transferase
|
–
–
–
|
MK
|
|
KEGG:
R02407
MetaCyc:
RXN-8987
|
|
|
|
ITP + Itaconate + CoA <=> IDP + phosphate + itaconyl-CoA
|
6.2.1.4
succinate---CoA ligase (GDP-forming)
|
–
|
|
|
KEGG:
R02406
|
|
|
|
acetyl-CoA + Itaconate <=> acetate + itaconyl-CoA
|
2.8.3
|
–
|
|
|
KEGG:
R10600
|
|
|
|
Itaconate <=> 2-Hydroxyparaconate
|
not assigned
|
–
|
K
|
|
KEGG:
R11750
|
|
|
|
Itaconate + O2 + reduced_[NADPH-hemoprotein_reductase] + H+ <=> 2-Hydroxyparaconate + H2O + oxidized_[NADPH-hemoprotein_reductase]
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-19903
|
|
|
|
citrate <=> Itaconate + CO2
|
4.1.1.6
cis-aconitate decarboxylase
|
–
|
|
|
BRENDA:
BS1514
|
|
|
|
D-isocitrate <=> Itaconate + CO2
|
4.1.1.6
cis-aconitate decarboxylase
|
–
|
|
|
BRENDA:
BS1513
|
|
|
|
Itaconate + NADH <=> (2R)-2-methylbutanedioic_acid + NAD+
|
1.3.1.31
2-enoate reductase
|
–
|
|
|
BRENDA:
BS395577-a
|
|
|
|
Itaconate <=> citraconate
|
5.3.3.6
methylitaconate Delta-isomerase
|
–
|
|
|
BRENDA:
BS409613
|
|
|
|
Itaconate + NADPH <=> (2R)-2-methylbutanedioic_acid + NADP+
|
1.3.1.31
2-enoate reductase
|
–
|
|
|
BRENDA:
BS395577
|
|